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Linking folding with aggregation in Alzheimer's β-amyloid peptides

Growing evidence suggests that the β-amyloid (Aβ) peptides of Alzheimer's disease are generated in early endosomes and that small oligomers are the principal toxic species. We sought to understand whether and how the solution pH, which is more acidic in endosomes than the extracellular environm...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Khandogin, Jana, Brooks, Charles L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040412/
https://ncbi.nlm.nih.gov/pubmed/17942695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703832104
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