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Internal and environmental effects on folding and dimerization of the Alzheimer’s β amyloid peptide
Amyloid deposits are a hallmark of many diseases. In the case of Alzheimer’s disease a turn between 21Ala and 30Ala, stabilized by a salt bridge between 22Glu/23Asp and 28Lys, may nucleate folding and aggregation of the Aβ peptide. In the present paper we test this hypothesis by studying how salt br...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3864693/ https://ncbi.nlm.nih.gov/pubmed/24353373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08927022.2011.551879 |
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