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The Role of Molecular Simulations in the Development of Inhibitors of Amyloid β-Peptide Aggregation for the Treatment of Alzheimer’s Disease

[Image: see text] The pathogenic aggregation of the amyloid β-peptide (Aβ) is considered a hallmark of the progression of Alzheimer’s disease, the leading cause of senile dementia in the elderly and one of the principal causes of death in the United States. In the absence of effective therapeutics,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lemkul, Justin A., Bevan, David R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2012
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503341/
https://ncbi.nlm.nih.gov/pubmed/23173066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300091a
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