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The Role of Molecular Simulations in the Development of Inhibitors of Amyloid β-Peptide Aggregation for the Treatment of Alzheimer’s Disease

[Image: see text] The pathogenic aggregation of the amyloid β-peptide (Aβ) is considered a hallmark of the progression of Alzheimer’s disease, the leading cause of senile dementia in the elderly and one of the principal causes of death in the United States. In the absence of effective therapeutics,...

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Bibliografiset tiedot
Päätekijät: Lemkul, Justin A., Bevan, David R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2012
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503341/
https://ncbi.nlm.nih.gov/pubmed/23173066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300091a
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