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Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes

The behavior of the amyloid β-peptide (Aβ) within a membrane environment is integral to its toxicity and the progression of Alzheimer's disease. Ganglioside GM1 has been shown to enhance the aggregation of Aβ, but the underlying mechanism is unknown. Using atomistic molecular dynamics simulatio...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lemkul, Justin A, Bevan, David R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley Subscription Services, Inc., A Wiley Company 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190148/
https://ncbi.nlm.nih.gov/pubmed/21692120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.678
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