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Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes
The behavior of the amyloid β-peptide (Aβ) within a membrane environment is integral to its toxicity and the progression of Alzheimer's disease. Ganglioside GM1 has been shown to enhance the aggregation of Aβ, but the underlying mechanism is unknown. Using atomistic molecular dynamics simulatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190148/ https://ncbi.nlm.nih.gov/pubmed/21692120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.678 |
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