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Alzheimer's disease β-amyloid peptides are released in association with exosomes

Although the exact etiology of Alzheimer's disease (AD) is a topic of debate, the consensus is that the accumulation of β-amyloid (Aβ) peptides in the senile plaques is one of the hallmarks of the progression of the disease. The Aβ peptide is formed by the amyloidogenic cleavage of the amyloid...

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Autori principali: Rajendran, Lawrence, Honsho, Masanori, Zahn, Tobias R., Keller, Patrick, Geiger, Kathrin D., Verkade, Paul, Simons, Kai
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544060/
https://ncbi.nlm.nih.gov/pubmed/16837572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603838103
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