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Familial Alzheimer’s Disease Mutations Differentially Alter Amyloid β-Protein Oligomerization
[Image: see text] Although most cases of Alzheimer’s disease (AD) are sporadic, ∼5% of cases are genetic in origin. These cases, known as familial Alzheimer’s disease (FAD), are caused by mutations that alter the rate of production or the primary structure of the amyloid β-protein (Aβ). Changes in t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3503339/ https://ncbi.nlm.nih.gov/pubmed/23173071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300050d |
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