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Tailored amino acid diversity for the evolution of antibody affinity

Antibodies are a unique class of proteins with the ability to adapt their binding sites for high affinity and high specificity to a multitude of antigens. Many analyses have been performed on antibody sequences and structures to elucidate which amino acids have a predominant role in antibody interac...

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Detalhes bibliográficos
Principais autores: González-Muñoz, Andrea, Bokma, Evert, O’Shea, Desmond, Minton, Kevin, Strain, Martin, Vousden, Katherine, Rossant, Christine, Jermutus, Lutz, Minter, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502233/
https://ncbi.nlm.nih.gov/pubmed/22926024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.21728
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