Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is a hereditary hamartoma syndrome that predisposes patients to develop hair follicle tumors, lung cysts, and kidney cancer. Genetic studies of BHD patients have uncovered the causative gene, FLCN, but its function is incompletely understood. METHODS: Mice w...

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Hauptverfasser: Hasumi, Hisashi, Baba, Masaya, Hasumi, Yukiko, Huang, Ying, Oh, Hyoungbin, Hughes, Robert M., Klein, Mara E., Takikita, Shoichi, Nagashima, Kunio, Schmidt, Laura S., Linehan, W. Marston
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502196/
https://ncbi.nlm.nih.gov/pubmed/23150719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs418
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