Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN

BACKGROUND: Birt-Hogg-Dubé (BHD) syndrome is a hereditary hamartoma syndrome that predisposes patients to develop hair follicle tumors, lung cysts, and kidney cancer. Genetic studies of BHD patients have uncovered the causative gene, FLCN, but its function is incompletely understood. METHODS: Mice w...

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Main Authors: Hasumi, Hisashi, Baba, Masaya, Hasumi, Yukiko, Huang, Ying, Oh, Hyoungbin, Hughes, Robert M., Klein, Mara E., Takikita, Shoichi, Nagashima, Kunio, Schmidt, Laura S., Linehan, W. Marston
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502196/
https://ncbi.nlm.nih.gov/pubmed/23150719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs418
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