Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis

Certain mutations within the mammalian target of rapamycin (mTOR) pathway, most notably those affecting the tuberous sclerosis complex (TSC), lead to aberrant activation of mTOR and result in a high incidence of epilepsy in humans and animal models. Although hyperactivation of mTOR has been strongly...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: McMahon, John, Huang, Xiaoxing, Yang, Jun, Komatsu, Masaaki, Yue, Zhenyu, Qian, Jiang, Zhu, Xinjun, Huang, Yunfei
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501684/
https://ncbi.nlm.nih.gov/pubmed/23136410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2392-12.2012
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker