Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

Inhibition of mTOR by rapamycin has been shown to suppress seizures in TSC/PTEN genetic models. Rapamycin, when applied immediately before or after a neurological insult, also prevents the development of spontaneous recurrent seizures (epileptogenesis) in an acquired model. In the present study, we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huang, Xiaoxing, Zhang, Hailong, Yang, Jun, Wu, Jingfan, McMahon, John, Lin, Yufan, Cao, Zhonglian, Gruenthal, Michael, Huang, Yunfei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926303/
https://ncbi.nlm.nih.gov/pubmed/20566381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.05.024
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