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Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy
Inhibition of mTOR by rapamycin has been shown to suppress seizures in TSC/PTEN genetic models. Rapamycin, when applied immediately before or after a neurological insult, also prevents the development of spontaneous recurrent seizures (epileptogenesis) in an acquired model. In the present study, we...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926303/ https://ncbi.nlm.nih.gov/pubmed/20566381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.05.024 |
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