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Proteasomal Degradation of Nod2 Protein Mediates Tolerance to Bacterial Cell Wall Components

The innate immune system serves as the first line of defense by detecting microbes and initiating inflammatory responses. Although both Toll-like receptor (TLR) and nucleotide binding domain and leucine-rich repeat (NLR) proteins are important for this process, their excessive activation is hazardou...

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Bibliografische gegevens
Hoofdauteurs: Lee, Kyoung-Hee, Biswas, Amlan, Liu, Yuen-Joyce, Kobayashi, Koichi S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501029/
https://ncbi.nlm.nih.gov/pubmed/23019338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410027
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