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Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
Mutations in the NOD2 gene are strong genetic risk factors for ileal Crohn’s disease. However, the mechanism by which these mutations predispose to intestinal inflammation remains a subject of controversy. We report that Nod2-deficient mice inoculated with Helicobacter hepaticus, an opportunistic pa...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930434/ https://ncbi.nlm.nih.gov/pubmed/20679225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003363107 |
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