NOD2, the Gene Responsible for Familial Granulomatous Uveitis, in a Mouse Model of Uveitis

PURPOSE: NOD2 plays an important role in the recognition of intracellular bacteria through its ability to sense the components of bacterial peptidoglycan (PGN), namely muramyl dipeptide (MDP) and muramyl tripeptide (MTP). Specific mutations in the human NOD2 gene cause Blau syndrome, an autosomal do...

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Auteurs principaux: Rosenzweig, Holly L., Martin, Tammy M., Jann, Monica M., Planck, Stephen R., Davey, Michael P., Kobayashi, Koichi, Flavell, Richard A., Rosenbaum, James T.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430189/
https://ncbi.nlm.nih.gov/pubmed/18385071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1174
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