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NOD2 Deficiency Results in Increased Susceptibility to Peptidoglycan-Induced Uveitis in Mice
PURPOSE. The innate immune receptor NOD2 is a genetic cause of uveitis (Blau syndrome). Intriguingly, in the intestine where polymorphisms of NOD2 predispose to Crohn's disease, NOD2 reportedly suppresses inflammation triggered by the bacterial cell wall component, peptidoglycan (PGN). Whether...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175939/ https://ncbi.nlm.nih.gov/pubmed/21296813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6263 |
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