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NOD2 Deficiency Results in Increased Susceptibility to Peptidoglycan-Induced Uveitis in Mice

PURPOSE. The innate immune receptor NOD2 is a genetic cause of uveitis (Blau syndrome). Intriguingly, in the intestine where polymorphisms of NOD2 predispose to Crohn's disease, NOD2 reportedly suppresses inflammation triggered by the bacterial cell wall component, peptidoglycan (PGN). Whether...

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Detaylı Bibliyografya
Asıl Yazarlar: Rosenzweig, Holly L., Galster, Kellen, Vance, Emily E., Ensign-Lewis, Joe, Nunez, Gabriel, Davey, Michael P., Rosenbaum, James T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Association for Research in Vision and Ophthalmology, Inc. 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175939/
https://ncbi.nlm.nih.gov/pubmed/21296813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6263
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