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NOD1 Expression in the Eye and Functional Contribution to IL-1β–Dependent Ocular Inflammation in Mice

PURPOSE: NOD1 plays an important role in host defense and recognizes the minimal component of bacterial cell walls, meso-diaminopimelic acid (iE-DAP). Polymorphisms in NOD1 are associated with autoinflammatory diseases characterized by uveitis such as Crohn’s disease and sarcoidosis. NOD1 is homolog...

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Main Authors: Rosenzweig, Holly L., Galster, Kellen T., Planck, Stephen R., Rosenbaum, James T.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086269/
https://ncbi.nlm.nih.gov/pubmed/19074813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2852
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