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Aberrant IL-1 signaling does not increase susceptibility of mice to NOD2-dependent uveitis

BACKGROUND: NOD2 is the genetic cause of Blau syndrome, an autoinflammatory disease that manifests as coincident uveitis and arthritis. Since dysregulation of IL-1 signaling is considered a pathogenic mechanism in a number of related autoinflammatory conditions, we examined the extent to which unimp...

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Detalhes bibliográficos
Publicado no:Clin Experiment Ophthalmol
Main Authors: Lee, Ellen L, Allensworth, Jordan J, Clowers, Jenna S, Rosenzweig, Holly L
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375092/
https://ncbi.nlm.nih.gov/pubmed/25255917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ceo.12438
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