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Biomimetic Synthesis and Biological Evaluation of Aplidiopsamine A

[Image: see text] The first total synthesis of Aplidiopsamine A, a rare 3H-pyrrolo[2,3-c]quinolone alkaloid from the Aplidiopsis confluata, has been achieved following the proposed biosynthesis. This biomimetic synthesis requires only 5 steps and proceeds in 20.8% overall yield. Biological evaluatio...

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Bibliographic Details
Main Authors: Panarese, Joseph D., Lindsley, Craig W.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500438/
https://ncbi.nlm.nih.gov/pubmed/23106227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3024665
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