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Regulation of CD4(+) and CD8(+) Effector Responses by Sprouty-1

TCR-induced NF-AT activation leads to the expression of both activating and inhibitory proteins. Previously, we had identified Egr-2 and Egr-3 as NF-AT-induced transcription factors which promote the inhibition of T cell activation. In this report we identify Sprouty1 as a downstream target of Egr-3...

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Autors principals: Collins, Sam, Waickman, Adam, Basson, Albert, Kupfer, Abraham, Licht, Jonathan D., Horton, Maureen R., Powell, Jonathan D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499516/
https://ncbi.nlm.nih.gov/pubmed/23166773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049801
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