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Genetic and biochemical regulation of CD4 T cell effector differentiation: insights from examination of T cell clonal anergy
The two-signal model of T cell activation states that antigen recognition by TCR provides a tolerogenic signal (termed Signal 1) unless the T cell receives simultaneous costimulation (Signal 2) that permits antigen recognition to prime activation. Our efforts to characterize genetic and biochemical...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892254/ https://ncbi.nlm.nih.gov/pubmed/20077160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-009-8147-0 |
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