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Anti-CD4 mediates clonal anergy during transplantation tolerance induction

Depletion of CD4+ cells using anti-CD4 monoclonal antibodies leads to allograft tolerance. Here we show that anti-CD4-mediated tolerance to pancreatic islets of Langerhans transplanted from an A/J (IEk) donor to a diabetic C57B1/6 (B6) (IE-) recipient occurs in the absence of clonal deletion of the...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118801/
https://ncbi.nlm.nih.gov/pubmed/1899105
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