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CD27 mediates interleukin-2-independent clonal expansion of the CD8(+) T cell without effector differentiation
The clonal expansion of antigen-specific CD8(+) T cells in response to microbial infections is essential for adaptive immunity. Although IL-2 has been considered to be primarily responsible for this process, quantitatively normal expansion occurs in the absence of IL-2 receptor signaling. Here, we s...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1697827/ https://ncbi.nlm.nih.gov/pubmed/17159138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609706104 |
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