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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Escherichia coli SeqA is a negative regulator of DNA replication that prevents premature reinitiation events by sequestering hemimethylated GATC clusters within the origin of replication(1). Beyond the origin, SeqA is found at the replication forks, where it organizes newly replicated DNA into highe...

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Autors principals: Chung, Yu Seon, Guarné, Alba
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499084/
https://ncbi.nlm.nih.gov/pubmed/23149570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4266
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