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Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein
The Escherichia coli SeqA protein recognizes the 11 hemimethylated G-(m)A-T-C sites in the oriC region of the chromosome, and prevents replication over-initiation within one cell cycle. The crystal structure of the SeqA C-terminal domain with hemimethylated DNA revealed the N(6)-methyladenine recogn...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373283/ https://ncbi.nlm.nih.gov/pubmed/14704346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh173 |
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