Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein

The Escherichia coli SeqA protein recognizes the 11 hemimethylated G-(m)A-T-C sites in the oriC region of the chromosome, and prevents replication over-initiation within one cell cycle. The crystal structure of the SeqA C-terminal domain with hemimethylated DNA revealed the N(6)-methyladenine recogn...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Fujikawa, Norie, Kurumizaka, Hitoshi, Nureki, Osamu, Tanaka, Yoshinori, Yamazoe, Mitsuyoshi, Hiraga, Sota, Yokoyama, Shigeyuki
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2004
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14704346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh173
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