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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Escherichia coli SeqA is a negative regulator of DNA replication that prevents premature reinitiation events by sequestering hemimethylated GATC clusters within the origin of replication(1). Beyond the origin, SeqA is found at the replication forks, where it organizes newly replicated DNA into highe...

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Hlavní autoři: Chung, Yu Seon, Guarné, Alba
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499084/
https://ncbi.nlm.nih.gov/pubmed/23149570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4266
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