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Calcium-dependent folding of single calmodulin molecules

Calmodulin is the primary calcium binding protein in living cells. Its function and structure depend strongly on calcium concentration. We used single molecule force spectroscopy by optical tweezers to study the folding of calmodulin in the physiologically relevant range. We find that full-length ca...

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Bibliografiske detaljer
Main Authors: Stigler, Johannes, Rief, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497792/
https://ncbi.nlm.nih.gov/pubmed/22753517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201801109
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