Single-Molecule Dynamics of the Calcium-Dependent Activation of Plasma-Membrane Ca(2+)-ATPase by Calmodulin

The plasma membrane calcium-ATPase (PMCA) helps to control cytosolic calcium levels by pumping out excess Ca(2+). PMCA is regulated by the Ca(2+) signaling protein calmodulin (CaM), which stimulates PMCA activity by binding to an autoinhibitory domain of PMCA. We used single-molecule polarization me...

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Détails bibliographiques
Auteurs principaux: Osborn, Kenneth D., Zaidi, Asma, Mandal, Abhijit, Urbauer, Ramona J. Bieber, Johnson, Carey K.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2004
Sujets:
Proteins
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304593/
https://ncbi.nlm.nih.gov/pubmed/15446271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.039404
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