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Mechanism of calmodulin recognition of the binding domain of isoform 1b of the plasma membrane Ca(2+)-ATPase: kinetic pathway and effects of methionine oxidation

Calmodulin (CaM) binds to a domain near the C-terminus of the plasma-membrane Ca(2+)-ATPase (PMCA), causing the release of this domain and relief of its autoinhibitory function. We investigated the kinetics of dissociation and binding of Ca(2+)-CaM with a 28-residue peptide (C28W(1b)) corresponding...

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Détails bibliographiques
Auteurs principaux: Slaughter, Brian D., Bieber Urbauer, Ramona J., Urbauer, Jeffrey L., Johnson, Carey K.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597417/
https://ncbi.nlm.nih.gov/pubmed/17343368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi602481u
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