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Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin
Aberrant activation of signaling by the Wnt pathway is strongly implicated in the onset and progression of numerous types of cancer. Owing to the persistent dependence of these tumors on Wnt signaling for growth and survival, inhibition of this pathway is considered an attractive mechanism-based the...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497784/ https://ncbi.nlm.nih.gov/pubmed/23071338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208396109 |
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