載入...
Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer
Aberrant regulation of the Wnt/β-catenin signaling pathway is one of the major causes of colorectal cancer (CRC). Loss-of-function mutations in APC are commonly found in CRC, leading to inappropriate activation of canonical Wnt signaling. Conversely, gain-of-function mutations in KRAS and BRAF genes...
Na minha lista:
| 發表在: | Oncogene |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2015
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687460/ https://ncbi.nlm.nih.gov/pubmed/25500543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.416 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|