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The Vpx Lentiviral Accessory Protein Targets SAMHD1 for Degradation in the Nucleus
Sterile alpha motif domain- and HD domain-containing protein 1 (SAMHD1) is a deoxynucleoside triphosphohydrolase that restricts the replication of lentiviruses in myeloid cells by hydrolyzing the cellular deoxynucleotide triphosphates to a level below that which is required for reverse transcription...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497686/ https://ncbi.nlm.nih.gov/pubmed/22973040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01657-12 |
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