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Degradation of SAMHD1 by Vpx Is Independent of Uncoating

Sterile alpha motif domain and HD domain-containing protein 1 (SAMHD1) restricts human immunodeficiency virus type 1 (HIV-1) replication in myeloid and resting T cells. Lentiviruses such as HIV-2 and some simian immunodeficiency viruses (SIVs) counteract the restriction by encoding Vpx or Vpr, acces...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Jáuregui, Paula, Logue, Eric C., Schultz, Megan L., Fung, Stephanie, Landau, Nathaniel R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442547/
https://ncbi.nlm.nih.gov/pubmed/25762741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03575-14
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