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HIV Type 1 Infection of Plasmacytoid and Myeloid Dendritic Cells Is Restricted by High Levels of SAMHD1 and Cannot be Counteracted by Vpx

Dendritic cells are professional antigen-presenting cells of the immune system and are major producers of type-I interferon. Their role in HIV-1 infection is not well understood. They express CD4 and CCR5 yet appear to be resistant to infection. In culture, infection of the cells with HIV-1 is inhib...

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Détails bibliographiques
Auteurs principaux: Bloch, Nicolin, O'Brien, Meagan, Norton, Thomas D., Polsky, Sylvie B., Bhardwaj, Nina, Landau, Nathaniel R.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910455/
https://ncbi.nlm.nih.gov/pubmed/23924154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2013.0119
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