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Human Immunodeficiency Virus Type 1 Modified To Package Simian Immunodeficiency Virus Vpx Efficiently Infects Macrophages and Dendritic Cells

The lentiviral accessory protein Vpx is thought to facilitate the infection of macrophages and dendritic cells by counteracting an unidentified host restriction factor. Although human immunodeficiency virus type 1 (HIV-1) does not encode Vpx, the accessory protein can be provided to monocyte-derived...

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Autors principals: Sunseri, Nicole, O'Brien, Meagan, Bhardwaj, Nina, Landau, Nathaniel R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126535/
https://ncbi.nlm.nih.gov/pubmed/21507971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00346-11
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