載入...

Initial Testing of the MDM2 Inhibitor RG7112 by the Pediatric Preclinical Testing Program

BACKGROUND: RG7112 is a selective inhibitor of p53-MDM2 binding that frees p53 from negative control, activating the p53 pathway in cancer cells leading to cell cycle arrest and apoptosis. RG7112 was selected for evaluation by the Pediatric Preclinical Testing Program (PPTP) due to the relatively lo...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Carol, Hernan, Reynolds, C. Patrick, Kang, Min H., Keir, Stephen T., Maris, John M., Gorlick, Richard, Kolb, E. Anders, Billups, Catherine A., Geier, Brian, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495996/
https://ncbi.nlm.nih.gov/pubmed/22753001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24235
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!