Serotonin-Induced Hypersensitivity via Inhibition of Catechol O-Methyltransferase Activity

The subcutaneous and systemic injection of serotonin reduces cutaneous and visceral pain thresholds and increases responses to noxious stimuli. Different subtypes of 5-hydroxytryptamine (5-HT) receptors are suggested to be associated with different types of pain responses. Here we show that serotoni...

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Autori principali: Tsao, Douglas, Wieskopf, Jeffrey S, Rashid, Naim, Sorge, Robert E, Redler, Rachel L, Segall, Samantha K, Mogil, Jeffrey S, Maixner, William, Dokholyan, Nikolay V, Diatchenko, Luda
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495668/
https://ncbi.nlm.nih.gov/pubmed/22500608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-25
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