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Increased Apopototic Chondrocytes in Articular Cartilage of Adults Heterozygous SirT1 Mice
OBJECTIVE: A growing body of evidence indicates that the protein deacetylase SirT1 affects chondrocyte biology and survival. This report aims to evaluate in-vivo effects of SirT1 on cartilage biology in 9 month-old mice 129/J murine strains. METHODS: Heterozygous (SirT1(+/−)) and wild type (WT; SirT...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495310/ https://ncbi.nlm.nih.gov/pubmed/22258484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2011.200504 |
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