A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4

AIMS: Pregnant women are usually not part of the traditional drug development programme. Pregnancy is associated with major biological and physiological changes that alter the pharmacokinetics (PK) of drugs. Prediction of the changes to drug exposure in this group of patients may help to prevent und...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gaohua, Lu, Abduljalil, Khaled, Jamei, Masoud, Johnson, Trevor N, Rostami-Hodjegan, Amin
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2012
Fag:
Drugs in Pregnancy and Lactation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495152/
https://ncbi.nlm.nih.gov/pubmed/22725721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04363.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker