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Efficient, Divergent Synthesis of Cryptophycin Unit A Analogues
A flexible and divergent synthesis of cryptophycin unit A analogues is described. This method relies on iridium-catalysed stereo- and enantioselective crotylation and chemoselective one-pot oxidative olefination to access common intermediate 8. Heck, cross metathesis, and Suzuki-Miyaura reactions ar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494784/ https://ncbi.nlm.nih.gov/pubmed/22617820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc32417b |
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