Llwytho...
shRNA suppression of thymidylate synthase produces DNA mismatches and results in excellent radiosensitization
PURPOSE: To determine the effect of shRNA-mediated suppression of thymidylate synthase (TS) on cytotoxicity and radiosensitization and the mechanism by which these events occur. METHODS AND MATERIALS: shRNA suppression of TS was compared to FdUrd inactivation of TS ± ionizing radiation in HCT116 and...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494755/ https://ncbi.nlm.nih.gov/pubmed/22867891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.06.050 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|