Anion channel blockers inhibit lysosomal enzyme secretion from human neutrophils without affecting generation of superoxide anion.

The role of permeant anions in lysosomal enzyme secretion from human neutrophils was investigated by means of anion-channel-blocking agents: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid (SITS), and pyridoxal phosphate. Lysosomal en...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Korchak, H M, Eisenstat, B A, Hoffstein, S T, Dunham, P B, Weissmann, G
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1980
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2721
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