Anion channel blockers inhibit lysosomal enzyme secretion from human neutrophils without affecting generation of superoxide anion.

The role of permeant anions in lysosomal enzyme secretion from human neutrophils was investigated by means of anion-channel-blocking agents: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid (SITS), and pyridoxal phosphate. Lysosomal en...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Korchak, H M, Eisenstat, B A, Hoffstein, S T, Dunham, P B, Weissmann, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2721
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