Anion channel blockers inhibit lysosomal enzyme secretion from human neutrophils without affecting generation of superoxide anion.

The role of permeant anions in lysosomal enzyme secretion from human neutrophils was investigated by means of anion-channel-blocking agents: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid (SITS), and pyridoxal phosphate. Lysosomal en...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Korchak, H M, Eisenstat, B A, Hoffstein, S T, Dunham, P B, Weissmann, G
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1980
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2721
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