Anion channel blockers inhibit lysosomal enzyme secretion from human neutrophils without affecting generation of superoxide anion.

The role of permeant anions in lysosomal enzyme secretion from human neutrophils was investigated by means of anion-channel-blocking agents: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid (SITS), and pyridoxal phosphate. Lysosomal en...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Korchak, H M, Eisenstat, B A, Hoffstein, S T, Dunham, P B, Weissmann, G
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1980
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6248861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.5.2721
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