Targeting the Acute Promyelocytic Leukemia-Associated Fusion Proteins PML/RARα and PLZF/RARα with Interfering Peptides

In acute promyelocytic leukemia (APL), hematopoietic differentiation is blocked and immature blasts accumulate in the bone marrow and blood. APL is associated with chromosomal aberrations, including t(15;17) and t(11;17). For these two translocations, the retinoic acid receptor alpha (RARα) is fused...

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Detaylı Bibliyografya
Asıl Yazarlar: Beez, Sabine, Demmer, Philipp, Puccetti, Elena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494703/
https://ncbi.nlm.nih.gov/pubmed/23152790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048636
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