Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

Fusion proteins involving the retinoic acid receptor alpha (RAR alpha) and the PML or PLZF nuclear protein are the genetic markers of acute promyelocytic leukemias (APLs). APLs with the PML-RAR alpha or the PLZF-RAR alpha fusion protein are phenotypically indistinguishable except that they differ in...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ruthardt, M, Testa, U, Nervi, C, Ferrucci, P F, Grignani, F, Puccetti, E, Peschle, C, Pelicci, P G
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC232338/
https://ncbi.nlm.nih.gov/pubmed/9234742
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