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Enhanced cancer cell killing by truncated E2F-1 used in combination with oncolytic adenovirus

Adenovirus-mediated gene transfer into a tumor mass can be improved by combining it with conditionally-replicating adenovirus (CRAd) when both vectors co-infect the same cancer cell. We investigated the efficiency of enhancing transgene expression and effectiveness of cancer killing of two advenovir...

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Detalhes bibliográficos
Main Authors: Gomez-Gutierrez, Jorge G., Rao, Xiao-Mei, Zhou, Heshan Sam, McMasters, Kelly M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494286/
https://ncbi.nlm.nih.gov/pubmed/23021422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.09.003
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