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Combination of autophagy inducer rapamycin and oncolytic adenovirus improves antitumor effect in cancer cells

BACKGROUND: Combination of oncolytic adenoviruses (Ads) and chemotherapy drugs has shown promising therapeutic results and is considered as a potential approach for cancer therapy. We previously have shown that autophagy may generate decomposed cellular molecules that can be used as nutrition to sup...

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Autors principals: Cheng, Pei-Hsin, Lian, Serena, Zhao, Robin, Rao, Xiao-Mei, McMasters, Kelly M, Zhou, Heshan Sam
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850263/
https://ncbi.nlm.nih.gov/pubmed/24059864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-293
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